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Pathway-Specific Analysis of Gene Expression Data Identifies the PI3K/Akt Pathway as a Novel Therapeutic Target in Cervical Cancer

PURPOSE: Cervical tumor response on posttherapy 2[(18)F]fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET) is predictive of survival outcome. The purpose of this study was to use gene expression profiling to identify pathways associated with tumor metabolic response. EXPERIMENTAL DESIGN...

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Detalhes bibliográficos
Main Authors: Schwarz, Julie K., Payton, Jacqueline E., Rashmi, Ramachandran, Xiang, Tao, Jia, Yunhe, Huettner, Phyllis, Rogers, Buck E., Yang, Qin, Watson, Mark, Rader, Janet S., Grigsby, Perry W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627483/
https://ncbi.nlm.nih.gov/pubmed/22235101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2485
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