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Mice Devoid of Tau Have Increased Susceptibility to Neuronal Damage in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis
The abundant axonal microtubule-associated protein tau regulates microtubule and actin dynamics, thereby contributing to normal neuronal function. We examined whether mice deficient in tau (Tau(−/−)) or with high levels of human tau differ from wild-type (WT) mice in their susceptibility to neuroaxo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627392/ https://ncbi.nlm.nih.gov/pubmed/22487860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3182540d2e |
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