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The Local Transcriptome in the Synaptic Neuropil Revealed by Deep Sequencing and High-Resolution Imaging

In neurons, dendritic protein synthesis is required for many forms of long-term synaptic plasticity. The population of mRNAs that are localized to dendrites, however, remains sparsely identified. Here, we use deep sequencing to identify the mRNAs resident in the synaptic neuropil in the hippocampus....

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Detalhes bibliográficos
Main Authors: Cajigas, Iván J., Tushev, Georgi, Will, Tristan J., Dieck, Susanne tom, Fuerst, Nicole, Schuman, Erin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627340/
https://ncbi.nlm.nih.gov/pubmed/22578497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.02.036
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