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The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway
Follicular B cell survival requires signaling from BAFFR, a receptor for BAFF and the B cell antigen receptor (BCR). This “tonic” BCR survival signal is distinct from that induced by antigen binding and may be ligand-independent. We show that inducible inactivation of the Syk tyrosine kinase, a key...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cell Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627223/ https://ncbi.nlm.nih.gov/pubmed/23453634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.11.015 |
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