The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
The tyrosine kinase P210 is the gene product of the rearranged BCR-ABL locus on the Philadelphia chromosome (Ph1), which is found in leukemic cells of patients with chronic myelogenous leukemia. It has a weakly oncogenic effect in immature murine hematopoietic cells and does not transform NIH 3T3 ce...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362717/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2725497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.3.1263-1270.1989 |
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