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The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.

The tyrosine kinase P210 is the gene product of the rearranged BCR-ABL locus on the Philadelphia chromosome (Ph1), which is found in leukemic cells of patients with chronic myelogenous leukemia. It has a weakly oncogenic effect in immature murine hematopoietic cells and does not transform NIH 3T3 ce...

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Bibliografske podrobnosti
Main Authors: Lugo, T G, Witte, O N
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC362717/
https://ncbi.nlm.nih.gov/pubmed/2725497
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