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The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.

The tyrosine kinase P210 is the gene product of the rearranged BCR-ABL locus on the Philadelphia chromosome (Ph1), which is found in leukemic cells of patients with chronic myelogenous leukemia. It has a weakly oncogenic effect in immature murine hematopoietic cells and does not transform NIH 3T3 ce...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Lugo, T G, Witte, O N
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 1989
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362717/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2725497/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.3.1263-1270.1989
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