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Detecting recurrent gene mutation in interaction network context using multi-scale graph diffusion

BACKGROUND: Delineating the molecular drivers of cancer, i.e. determining cancer genes and the pathways which they deregulate, is an important challenge in cancer research. In this study, we aim to identify pathways of frequently mutated genes by exploiting their network neighborhood encoded in the...

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Bibliografiske detaljer
Main Authors: Babaei, Sepideh, Hulsman, Marc, Reinders, Marcel, Ridder, Jeroen de
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626877/
https://ncbi.nlm.nih.gov/pubmed/23343428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-29
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