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Drug Release Kinetics, Cell Uptake, and Tumor Toxicity of Hybrid VVVVVVKK Peptide-Assembled Polylactide Nanoparticles

An exciting approach to tumor delivery is encapsulation of the drug in self-assembled polymer-peptide nanoparticles. The objective of this work was to synthesize a conjugate of low molecular weight polylactide (LMW PLA) and V6K2 peptide, and investigate self-assembly, drug release kinetics, cell upt...

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Detalhes bibliográficos
Main Authors: Jabbari, Esmaiel, Yang, Xiaoming, Moeinzadeh, Seyedsina, He, Xuezhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626769/
https://ncbi.nlm.nih.gov/pubmed/23275111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2012.12.012
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