Release Characteristics and Osteogenic Activity of Recombinant Human Bone Morphogenetic Protein-2 grafted to Novel Self-Assembled Poly(lactide-co-glycolide fumarate) Nanoparticles

Functionalized biodegradable nanoparticles (NPs) provide reactive groups and large surface area for grafting Recombinant human bone morphogenetic protein-2 (rhBMP-2) to reduce protein diffusion and maintain sufficient concentration for recruitment and differentiation of osteoprogenitor cells. The ob...

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Hlavní autoři: Mercado, Angel E, Ma, Junyu, He, Xuezhong, Jabbari, Esmaiel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783665/
https://ncbi.nlm.nih.gov/pubmed/19699244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.08.009
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