Retrovirus-mediated transfer and expression of the interleukin-3 gene in mouse hematopoietic cells result in a myeloproliferative disorder.

A high-titer, recombinant retroviral vector produced in psi 2 packaging cells has been used to introduce the murine interleukin-3 (IL-3) gene into mouse hematopoietic cells. Integration and expression of the IL-3 gene was observed in spleen foci from which could be derived factor-independent, contin...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Wong, P M, Chung, S W, Dunbar, C E, Bodine, D M, Ruscetti, S, Nienhuis, A W
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 1989
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362657/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2565534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.2.798-808.1989
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