Retrovirus-mediated transfer and expression of the interleukin-3 gene in mouse hematopoietic cells result in a myeloproliferative disorder.

A high-titer, recombinant retroviral vector produced in psi 2 packaging cells has been used to introduce the murine interleukin-3 (IL-3) gene into mouse hematopoietic cells. Integration and expression of the IL-3 gene was observed in spleen foci from which could be derived factor-independent, contin...

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Bibliografiska uppgifter
Huvudupphovsmän: Wong, P M, Chung, S W, Dunbar, C E, Bodine, D M, Ruscetti, S, Nienhuis, A W
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1989
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC362657/
https://ncbi.nlm.nih.gov/pubmed/2565534
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