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Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes

Previous studies have attempted to define human leukocyte antigen (HLA) class II supertypes, analogous to the case for class I, on the basis of shared peptide-binding motifs or structure. In the present study, we determined the binding capacity of a large panel of non-redundant peptides for a set of...

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Détails bibliographiques
Auteurs principaux: Greenbaum, Jason, Sidney, John, Chung, Jolan, Brander, Christian, Peters, Bjoern, Sette, Alessandro
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626422/
https://ncbi.nlm.nih.gov/pubmed/21305276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-011-0513-0
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