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Definition of the human raf amino-terminal regulatory region by deletion mutagenesis.

Activation of transforming potential of the cellular raf gene has uniformly been associated with the deletion of amino-terminal coding sequences. In order to determine whether 5' truncation alone could activate cellular raf, we constructed 21 human c-raf-1 cDNAs with variable BAL 31-generated d...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Stanton, V P, Nichols, D W, Laudano, A P, Cooper, G M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362641/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2710120/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.2.639
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