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Arginine-based cationic liposomes for efficient in vitro plasmid DNA delivery with low cytotoxicity
BACKGROUND: Currently available gene delivery vehicles have many limitations such as low gene delivery efficiency and high cytotoxicity. To overcome these drawbacks, we designed and synthesized two cationic lipids comprised of n-tetradecyl alcohol as the hydrophobic moiety, 3-hydrocarbon chain as th...
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| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3626367/ https://ncbi.nlm.nih.gov/pubmed/23630419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S38903 |
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