Arginine-based cationic liposomes for efficient in vitro plasmid DNA delivery with low cytotoxicity

BACKGROUND: Currently available gene delivery vehicles have many limitations such as low gene delivery efficiency and high cytotoxicity. To overcome these drawbacks, we designed and synthesized two cationic lipids comprised of n-tetradecyl alcohol as the hydrophobic moiety, 3-hydrocarbon chain as th...

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Autores principales: Sarker, Satya Ranjan, Aoshima, Yumiko, Hokama, Ryosuke, Inoue, Takafumi, Sou, Keitaro, Takeoka, Shinji
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2013
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626367/
https://ncbi.nlm.nih.gov/pubmed/23630419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S38903
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