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Regulation of SPARC by Transforming Growth Factor β2 in Human Trabecular Meshwork

PURPOSE. An increased aqueous level of TGF-β2 has been found in many primary open-angle glaucoma patients. Secreted Protein, Acidic, and Rich in Cysteine (SPARC)-null mice have a lower intraocular pressure. The mechanistic relationship between SPARC and TGF-β2 in trabecular meshwork (TM) is unknown....

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Main Authors: Kang, Min Hyung, Oh, Dong-Jin, Kang, Ja-heon, Rhee, Douglas J.
Formato: Artigo
Idioma:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626313/
https://ncbi.nlm.nih.gov/pubmed/23513064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11474
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