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Pharmacological Regulation of SPARC by Lovastatin in Human Trabecular Meshwork Cells
PURPOSE. Statins have been shown to increase aqueous outflow facility. The matricellular protein SPARC (secreted protein acidic and rich in cysteine) is a critical mediator of aqueous outflow and intraocular pressure (IOP). Here, we examine the effects of lovastatin on SPARC expression in trabecular...
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| 出版年: | Invest Ophthalmol Vis Sci |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Association for Research in Vision and Ophthalmology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586968/ https://ncbi.nlm.nih.gov/pubmed/24474275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12712 |
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