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Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae.

Two mutant alleles of RAS2 were discovered that dominantly interfere with wild-type RAS function in the yeast Saccharomyces cerevisiae. An amino acid substitution which caused the dominant interference was an alanine for glycine at position 22 or a proline for alanine at position 25. Analogous mutat...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Powers, S, O'Neill, K, Wigler, M
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362613/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2651897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.2.390
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