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Ivacaftor: A Novel Gene-Based Therapeutic Approach for Cystic Fibrosis

Ivacaftor is a new therapeutic agent that acts at the cystic fibrosis transmembrane conductance regulator (CFTR) channel to alter activity. It is approved for use in patients 6 years and older with cystic fibrosis who have at least 1 G551D mutation in the CFTR gene. It is unlike any other current ph...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Condren, Michelle E., Bradshaw, Marquita D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Pediatric Pharmacy Advocacy Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626070/
https://ncbi.nlm.nih.gov/pubmed/23616732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-18.1.8
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