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Sequences downstream of AAUAAA signals affect pre-mRNA cleavage and polyadenylation in vitro both directly and indirectly.

To investigate the role of sequences lying downstream of the conserved AAUAAA hexanucleotide in pre-mRNA cleavage and polyadenylation, deletions or substitutions were constructed in polyadenylation signals from simian virus 40 and adenovirus, and their effects were assayed in both crude and fraction...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Ryner, L C, Takagaki, Y, Manley, J L
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362595/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2566911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1759-1771.1989
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