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Supramolecular protein cage composite MR contrast agents with extremely efficient relaxivity properties

A DTPA-Gd containing polymer was grown in the interior of a heat shock protein cage resulting in T(1) particle relaxivities of 4,200mM(-1) sec(-1) for the 12nm particle. Relaxivity parameters were determined and this analysis suggests that the rotational correlation time has been optimized while the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liepold, Lars O, Abedin, Joynal, Buckhouse, Emily D, Frank, Joseph A., Young, Mark J., Douglas, Trevor
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625947/
https://ncbi.nlm.nih.gov/pubmed/19888720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl902884p
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