Naturally occurring autoantibodies interfere with β-amyloid metabolism and improve cognition in a transgenic mouse model of Alzheimer's disease 24 h after single treatment

There is evidence that naturally occurring antibodies directed against Aβ (nAbs-Aβ) have a role in Aβ-metabolism and Aβ-clearance. The presence of nAbs-Aβ leads to a reduction in amyloid fibrillation and thus a reduction in their toxicity. We investigated the effects of nAbs-Aβ in respect to oligome...

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Detalhes bibliográficos
Main Authors: Mengel, D, Röskam, S, Neff, F, Balakrishnan, K, Deuster, O, Gold, M, Oertel, W H, Bacher, M, Bach, J-P, Dodel, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625912/
https://ncbi.nlm.nih.gov/pubmed/23462987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.151
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