Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression

Myocardial depression is an important contributor to morbidity and mortality in septic patients. Nitric oxide (NO) plays an important role in the development of septic cardiomyopathy, but also has protective effects. Recent evidence has indicated that NO exerts many of its downstream effects on the...

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Autori principali: Sips, Patrick Y., Irie, Tomoya, Zou, Lin, Shinozaki, Shohei, Sakai, Michihiro, Shimizu, Nobuyuki, Nguyen, Rebecca, Stamler, Jonathan S., Chao, Wei, Kaneki, Masao, Ichinose, Fumito
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
Soggetti:
Integrative Cardiovascular Physiology and Pathophysiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625910/
https://ncbi.nlm.nih.gov/pubmed/23417863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00887.2012
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