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Muscle metaboreflex-induced coronary vasoconstriction limits ventricular contractility during dynamic exercise in heart failure

Muscle metaboreflex activation (MMA) during dynamic exercise increases cardiac work and myocardial O(2) demand via increases in heart rate, ventricular contractility, and afterload. This increase in cardiac work should lead to metabolic coronary vasodilation; however, no change in coronary vascular...

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Detalhes bibliográficos
Main Authors: Coutsos, Matthew, Sala-Mercado, Javier A., Ichinose, Masashi, Li, ZhenHua, Dawe, Elizabeth J., O'Leary, Donal S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625893/
https://ncbi.nlm.nih.gov/pubmed/23355344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00879.2012
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