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RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells
We have utilized retinoic acid receptor γ (gamma) knockout (RARγ(−/−)) embryonic stem (ES) cells as a model system to analyze RARγ mediated transcriptional regulation of stem cell differentiation. Most of the transcripts regulated by all-trans retinoic acid (RA) in ES cells are dependent upon functi...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Company of Biologists
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625813/ https://ncbi.nlm.nih.gov/pubmed/23264745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.119701 |
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