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Efficient acquisition of high-resolution 4-D diagonal-suppressed methyl–methyl NOESY for large proteins
The methyl–methyl NOESY experiment plays an important role in determining the global folds of large proteins. Despite the high sensitivity of this experiment, the analysis of methyl–methyl NOEs is frequently hindered by the limited chemical shift dispersion of methyl groups, particularly methyl prot...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625671/ https://ncbi.nlm.nih.gov/pubmed/22464875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmr.2012.02.021 |
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