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Rapid Protein Global Fold Determination Using Ultrasparse Sampling, High-Dynamic Range Artifact Suppression, and Time-Shared NOESY

In structural studies of large proteins by NMR, global fold determination plays an increasingly important role in providing a first look at a target’s topology and reducing assignment ambiguity in NOESY spectra of fully-protonated samples. In this work, we demonstrate the use of ultrasparse sampling...

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Autors principals: Coggins, Brian E., Werner-Allen, Jonathan W., Yan, Anthony, Zhou, Pei
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535273/
https://ncbi.nlm.nih.gov/pubmed/22946863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307445y
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