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Quantitative measurements and modeling of cargo–motor interactions during fast transport in the living axon

The kinesins have long been known to drive microtubule-based transport of sub-cellular components, yet the mechanisms of their attachment to cargo remain a mystery. Several different cargo-receptors have been proposed based on their in vitro binding affinities to kinesin-1. Only two of these—phospha...

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Bibliographic Details
Main Authors: Seamster, Pamela E, Loewenberg, Michael, Pascal, Jennifer, Chauviere, Arnaud, Gonzales, Aaron, Cristini, Vittorio, Bearer, Elaine L
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625656/
https://ncbi.nlm.nih.gov/pubmed/23011729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/9/5/055005
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