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Axonal transport cargo motor count versus average transport velocity: Is fast versus slow transport really single versus multiple motor transport?

Cargos have been observed exhibiting a “stop-and-go” behavior (i.e. cargo “pause”), and it has generally been assumed that these multi-second pauses can be attributed to equally long pauses of cargo-bound motors during motor procession. We contend that a careful examination of the isolated microtubu...

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Détails bibliographiques
Publié dans:J Theor Biol
Auteurs principaux: Lee, Robert H., Mitchell, Cassie S.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359950/
https://ncbi.nlm.nih.gov/pubmed/25615423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2015.01.010
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