FISH Detection of PML-RARA Fusion in ins(15;17) Acute Promyelocytic Leukaemia Depends on Probe Size

The diagnosis of acute promyelocytic leukaemia (APL) is usually confirmed by cytogenetics showing the characteristic t(15;17), but a minority of patients have a masked PML/RARA fusion. We report ten patients with APL and no evidence of the t(15;17), in whom the insertion of RARA into PML could not b...

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Main Authors: Campbell, Lynda J., Oei, Paul, Brookwell, Ross, Shortt, Jake, Eaddy, Nicola, Ng, Ashley, Chew, Edward, Browett, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625549/
https://ncbi.nlm.nih.gov/pubmed/23607089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/164501
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