Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA

BACKGROUND: Combined treatment with all-trans-retinoic acid and chemotherapy is extremely efficient in patients with acute promyelocytic leukemia with t(15;17)/PML-RARA, but up to 15% of patients relapse. DESIGN AND METHODS: To further clarify the prognostic impact of parameters such as FLT3 mutatio...

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Main Authors: Schnittger, Susanne, Bacher, Ulrike, Haferlach, Claudia, Kern, Wolfgang, Alpermann, Tamara, Haferlach, Torsten
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2011
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232262/
https://ncbi.nlm.nih.gov/pubmed/21859732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.049007
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