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P. gingivalis-Nucleoside-diphosphate-kinase Inhibits ATP-Induced Reactive-Oxygen-Species via P2X(7) Receptor/NADPH-Oxidase Signaling and Contributes to Persistence
Ligation of P2X(7) receptors with a “danger signal”, extracellular ATP (eATP), has recently been shown to result in production of intracellular reactive-oxygen-species (ROS) in macrophages. We show that primary gingival epithelial cells (GECs) produce sustained, robust cellular ROS upon stimulation...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625498/ https://ncbi.nlm.nih.gov/pubmed/23241000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12089 |
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