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PET Imaging of CD105/Endoglin Expression with a (61/64)Cu-Labeled Fab Antibody Fragment

PURPOSE: The goal of this study was to generate and characterize the Fab fragment of TRC105, a monoclonal antibody that binds with high affinity to human and murine CD105 (i.e. endoglin), and investigate its potential for positron emission tomography (PET) imaging of tumor angiogenesis in a small an...

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Detalles Bibliográficos
Main Authors: Zhang, Yin, Hong, Hao, Orbay, Hakan, Valdovinos, Hector F., Nayak, Tapas R., Theuer, Charles P., Barnhart, Todd E., Cai, Weibo
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625465/
https://ncbi.nlm.nih.gov/pubmed/23344138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-012-2334-2
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