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Positron Emission Tomography Imaging of Tumor Angiogenesis with a (61/64)Cu-Labeled F(ab')(2) Antibody Fragment

The objective of this study was to characterize the in vitro and in vivo properties of the F(ab')(2) fragment of TRC105, a human/murine chimeric IgG1 monoclonal antibody that binds with high avidity to human and murine CD105 (i.e. endoglin), and investigate its potential for positron emission t...

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Hlavní autoři: Hong, Hao, Zhang, Yin, Orbay, Hakan, Valdovinos, Hector F., Nayak, Tapas R., Bean, Jero, Theuer, Charles P., Barnhart, Todd E., Cai, Weibo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563848/
https://ncbi.nlm.nih.gov/pubmed/23316869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300507r
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