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Positron Emission Tomography Imaging of Tumor Angiogenesis with a (61/64)Cu-Labeled F(ab')(2) Antibody Fragment

The objective of this study was to characterize the in vitro and in vivo properties of the F(ab')(2) fragment of TRC105, a human/murine chimeric IgG1 monoclonal antibody that binds with high avidity to human and murine CD105 (i.e. endoglin), and investigate its potential for positron emission t...

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Autors principals: Hong, Hao, Zhang, Yin, Orbay, Hakan, Valdovinos, Hector F., Nayak, Tapas R., Bean, Jero, Theuer, Charles P., Barnhart, Todd E., Cai, Weibo
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563848/
https://ncbi.nlm.nih.gov/pubmed/23316869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300507r
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