Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

BACKGROUND: Genome-wide association studies have identified at least 15 independent common genetic variants associated with colorectal cancer (CRC) risk. The aim of this study was to investigate whether 11 of these variants are associated with CRC risk for carriers of germline mutations in DNA misma...

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Hauptverfasser: Win, Aung Ko, Hopper, John L., Buchanan, Daniel D., Young, Joanne P., Tenesa, Albert, Dowty, James G., Giles, Graham G., Goldblatt, Jack, Winship, Ingrid, Boussioutas, Alex, Young, Graeme P., Parry, Susan, Baron, John A., Duggan, David, Gallinger, Steven, Newcomb, Polly A., Haile, Robert W., Le Marchand, Loïc, Lindor, Noralane M., Jenkins, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625445/
https://ncbi.nlm.nih.gov/pubmed/23434150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2013.01.029
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