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Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

BACKGROUND: Genome-wide association studies have identified at least 15 independent common genetic variants associated with colorectal cancer (CRC) risk. The aim of this study was to investigate whether 11 of these variants are associated with CRC risk for carriers of germline mutations in DNA misma...

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Détails bibliographiques
Auteurs principaux: Win, Aung Ko, Hopper, John L., Buchanan, Daniel D., Young, Joanne P., Tenesa, Albert, Dowty, James G., Giles, Graham G., Goldblatt, Jack, Winship, Ingrid, Boussioutas, Alex, Young, Graeme P., Parry, Susan, Baron, John A., Duggan, David, Gallinger, Steven, Newcomb, Polly A., Haile, Robert W., Le Marchand, Loïc, Lindor, Noralane M., Jenkins, Mark A.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625445/
https://ncbi.nlm.nih.gov/pubmed/23434150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2013.01.029
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