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Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis

Osteoarthritis is a complex disease involving the mechanical breakdown of articular cartilage in the presence of altered joint mechanics and chondrocyte death, but the connection between these factors is not well established. Lubricin, a mucinous glycoprotein encoded by the PRG4 gene, provides bound...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Waller, Kimberly A., Zhang, Ling X., Elsaid, Khaled A., Fleming, Braden C., Warman, Matthew L., Jay, Gregory D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625316/
https://ncbi.nlm.nih.gov/pubmed/23530215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219289110
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