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FCGR2B and FCRLB Gene Polymorphisms Associated with IgA Nephropathy

BACKGROUND: IgA nephropathy (IgAN) is a complex syndrome characterized by deposition of IgA and IgA containing immune complexes (ICs) composed of IgG and complement C3 proteins in the mesangial area of glomeruli. The low-affinity receptors for the Fc region of IgG (FcγRs) are involved in autoantibod...

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Detalhes bibliográficos
Main Authors: Zhou, Xu-jie, Cheng, Fa-juan, Qi, Yuan-yuan, Zhao, Yan-feng, Hou, Ping, Zhu, Li, Lv, Ji-cheng, Zhang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625155/
https://ncbi.nlm.nih.gov/pubmed/23593433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061208
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