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Possible involvement of normal p21 H-ras in the insulin/insulinlike growth factor 1 signal transduction pathway.

Expression of a mutant H-ras gene confers a transformed phenotype to rat-1 fibroblasts which is basically independent of exogenous growth factors (GFs). Rat-1 cells induced to express high levels of the normal H-ras gene were also found to display a transformed phenotype. In contrast to cells expres...

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Udgivet i:Mol Cell Biol
Principais autores: Burgering, B M, Snijders, A J, Maassen, J A, van der Eb, A J, Bos, J L
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362512/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.10.4312-4322.1989
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