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Matrix metalloproteinase-9 deficiency leads to prolonged foreign body response in the brain associated with increased IL-1β levels and leakage of the blood brain barrier
Matrix metalloproteinases (MMPs) are enzymes with specificity towards extracellular matrix (ECM) components. MMPs, especially MMP-9, have been shown to degrade components of the basal lamina and disrupt the blood-brain barrier (BBB) and thus, contribute to neuroinflammation. In the present study we...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624973/ https://ncbi.nlm.nih.gov/pubmed/19264129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2009.02.002 |
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