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Endogenous activation of presynaptic NMDA receptors enhances glutamate release from the primary afferents in the spinal dorsal horn in a rat model of neuropathic pain
Activation of N-methyl-d-aspartate (NMDA) receptors (NMDARs) is a crucial mechanism underlying the development and maintenance of pain. Traditionally, the role of NMDARs in the pathogenesis of pain is ascribed to their activation and signalling cascades in postsynaptic neurons. In this study, we det...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624865/ https://ncbi.nlm.nih.gov/pubmed/23359671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.250522 |
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