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Gating of long-term depression by Ca(2+)/calmodulin-dependent protein kinase II through enhanced cGMP signalling in cerebellar Purkinje cells

Long-term depression (LTD) at parallel fibre synapses on a cerebellar Purkinje cell has been regarded as a cellular basis for motor learning. Although Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) has been implicated in the LTD induction as an important Ca(2+)-sensing molecule, the underlyi...

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Detalhes bibliográficos
Main Authors: Kawaguchi, Shin-ya, Hirano, Tomoo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624847/
https://ncbi.nlm.nih.gov/pubmed/23297306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.245787
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