EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments

Motivation: Messenger RNA expression is important in normal development and differentiation, as well as in manifestation of disease. RNA-seq experiments allow for the identification of differentially expressed (DE) genes and their corresponding isoforms on a genome-wide scale. However, statistical m...

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Detalhes bibliográficos
Main Authors: Leng, Ning, Dawson, John A., Thomson, James A., Ruotti, Victor, Rissman, Anna I., Smits, Bart M. G., Haag, Jill D., Gould, Michael N., Stewart, Ron M., Kendziorski, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624807/
https://ncbi.nlm.nih.gov/pubmed/23428641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt087
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