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Ebselen Alters Mitochondrial Physiology and Reduces Viability of Rat Hippocampal Astrocytes

The seleno-organic compound and radical scavenger ebselen (2-phenyl-1,2-benzisoselenazol-3(2H)-one) have been extensively employed as an anti-inflammatory and neuroprotective compound. However, its glutathione peroxidase activity at the expense of cellular thiols groups could underlie certain delete...

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Autors principals: Santofimia-Castaño, Patricia, Salido, Ginés M., González, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624633/
https://ncbi.nlm.nih.gov/pubmed/23496767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2012.1939
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