Cysteine-rich Domain 1 of CD40 Mediates Receptor Self-assembly

The activation of CD40 on B cells, macrophages, and dendritic cells by its ligand CD154 (CD40L) is essential for the development of humoral and cellular immune responses. CD40L and other TNF superfamily ligands are noncovalent homotrimers, but the form under which CD40 exists in the absence of ligan...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Smulski, Cristian R., Beyrath, Julien, Decossas, Marion, Chekkat, Neila, Wolff, Philippe, Estieu-Gionnet, Karine, Guichard, Gilles, Speiser, Daniel, Schneider, Pascal, Fournel, Sylvie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624471/
https://ncbi.nlm.nih.gov/pubmed/23463508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.427583
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky