Medium-chain Fatty Acid-sensing Receptor, GPR84, Is a Proinflammatory Receptor

G protein-coupled receptor 84 (GPR84) is a putative receptor for medium-chain fatty acids (MCFAs), whose pathophysiological roles have not yet been clarified. Here, we show that GPR84 was activated by MCFAs with the hydroxyl group at the 2- or 3-position more effectively than nonhydroxylated MCFAs....

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Detaylı Bibliyografya
Asıl Yazarlar: Suzuki, Masakatsu, Takaishi, Sachiko, Nagasaki, Miyuki, Onozawa, Yoshiko, Iino, Ikue, Maeda, Hiroaki, Komai, Tomoaki, Oda, Tomiichiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2013
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624448/
https://ncbi.nlm.nih.gov/pubmed/23449982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420042
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