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Medium-chain Fatty Acid-sensing Receptor, GPR84, Is a Proinflammatory Receptor
G protein-coupled receptor 84 (GPR84) is a putative receptor for medium-chain fatty acids (MCFAs), whose pathophysiological roles have not yet been clarified. Here, we show that GPR84 was activated by MCFAs with the hydroxyl group at the 2- or 3-position more effectively than nonhydroxylated MCFAs....
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624448/ https://ncbi.nlm.nih.gov/pubmed/23449982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420042 |
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