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Inhibition of Nucleotide Sugar Transport in Trypanosoma brucei Alters Surface Glycosylation

Nucleotide sugar transporters (NSTs) are indispensible for the biosynthesis of glycoproteins by providing the nucleotide sugars needed for glycosylation in the lumen of the Golgi apparatus. Mutations in NST genes cause human and cattle diseases and impaired cell walls of yeast and fungi. Information...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Li, Xu, Yu-Xin, Caradonna, Kacey L., Kruzel, Emilia K., Burleigh, Barbara A., Bangs, James D., Hirschberg, Carlos B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624441/
https://ncbi.nlm.nih.gov/pubmed/23443657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.453597
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