Nicotinamide Inhibits the Lysosomal Cathepsin b-like Protease and Kills African Trypanosomes

Nicotinamide, a soluble compound of the vitamin B(3) group, has antimicrobial activity against several microorganisms ranging from viruses to parasite protozoans. However, the mode of action of this antimicrobial activity is unknown. Here, we investigate the trypanocidal activity of nicotinamide on...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Unciti-Broceta, Juan D., Maceira, José, Morales, Sonia, García-Pérez, Angélica, Muñóz-Torres, Manuel E., Garcia-Salcedo, Jose A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Microbiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624436/
https://ncbi.nlm.nih.gov/pubmed/23443665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.449207
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